Understanding the structure and function of catalases: clues from molecular evolution and in vitro mutagenesis.

  title={Understanding the structure and function of catalases: clues from molecular evolution and in vitro mutagenesis.},
  author={Marcel Z{\'a}mock{\'y} and Franz Koller},
  journal={Progress in biophysics and molecular biology},
  volume={72 1},
This review gives an overview about the structural organisation of different evolutionary lines of all enzymes capable of efficient dismutation of hydrogen peroxide. Major potential applications in biotechnology and clinical medicine justify further investigations. According to structural and functional similarities catalases can be divided in three subgroups. Typical catalases are homotetrameric haem proteins. The three-dimensional structure of six representatives has been resolved to atomic… CONTINUE READING


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