Understanding the process of corneal endothelial morphological change in vitro.

  title={Understanding the process of corneal endothelial morphological change in vitro.},
  author={Olivier Roy and V{\'e}ronique Beaulieu Leclerc and Jean-Michel Bourget and Mathieu Th{\'e}riault and St{\'e}phanie Proulx},
  journal={Investigative ophthalmology & visual science},
  volume={56 2},
Corneal endothelial cells often adopt a fibroblastic-like morphology in culture, a process that has been attributed to epithelial- or endothelial-to-mesenchymal transition (EMT or EndMT). Although being extensively studied in other cell types, this transition is less well characterized in the corneal endothelium. Because of their neuroectodermal origin and their in vivo mitotic arrest, corneal endothelial cells represent a particular tissue that deserves more attention. This review article… CONTINUE READING


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