Understanding the molecular basis of sperm capacitation through kinase design.

@article{Visconti2009UnderstandingTM,
  title={Understanding the molecular basis of sperm capacitation through kinase design.},
  author={Pablo E Visconti},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2009},
  volume={106 3},
  pages={
          667-8
        }
}
Thirty years ago, on July 25, Steptoe and Edwards reported the birth of Louise Joy Brown, the first successful “Test-Tube” baby (1). This achievement followed a lack of success of in vitro fertilization experiments for almost 80 years since the first attempts in 1878. These early failures were due mainly to a lack of comprehension of sperm physiology. In the early 1950s, Chang (2) and Austin (3) demonstrated independently that sperm had to be in the female reproductive tract for a finite period… CONTINUE READING

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