Understanding the molecular basis of sperm capacitation through kinase design

  title={Understanding the molecular basis of sperm capacitation through kinase design},
  author={P. Visconti},
  journal={Proceedings of the National Academy of Sciences},
  pages={667 - 668}
  • P. Visconti
  • Published 2009
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • Thirty years ago, on July 25, Steptoe and Edwards reported the birth of Louise Joy Brown, the first successful “Test-Tube” baby (1). This achievement followed a lack of success of in vitro fertilization experiments for almost 80 years since the first attempts in 1878. These early failures were due mainly to a lack of comprehension of sperm physiology. In the early 1950s, Chang (2) and Austin (3) demonstrated independently that sperm had to be in the female reproductive tract for a finite period… CONTINUE READING
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