Understanding the mechanisms and drivers of antimicrobial resistance

  title={Understanding the mechanisms and drivers of antimicrobial resistance},
  author={A. Holmes and L. Moore and A. Sundsfjord and M. Steinbakk and L. Piddock},
  journal={The Lancet},
  • A. Holmes, L. Moore, +2 authors L. Piddock
  • Published 2016
  • Biology, Engineering, Medicine
  • The Lancet
  • To combat the threat to human health and biosecurity from antimicrobial resistance, an understanding of its mechanisms and drivers is needed. Emergence of antimicrobial resistance in microorganisms is a natural phenomenon, yet antimicrobial resistance selection has been driven by antimicrobial exposure in health care, agriculture, and the environment. Onward transmission is affected by standards of infection control, sanitation, access to clean water, access to assured quality antimicrobials… CONTINUE READING
    775 Citations
    Antimicrobial Resistance: a One Health Perspective.
    • 56
    • PDF
    Antimicrobial Resistance in Bacteria: Mechanisms, Evolution, and Persistence
    • 15
    One Health—Its Importance in Helping to Better Control Antimicrobial Resistance
    • 40
    • PDF
    Antimicrobial Stewardship: Fighting Antimicrobial Resistance and Protecting Global Public Health
    • Highly Influenced
    • PDF
    Antimicrobial resistance – moving forward?
    • 10
    • PDF
    Antimicrobial Resistance in Veterinary Medicine: An Overview
    • 12
    • PDF


    Spread of resistant bacteria and resistance genes from animals to humans--the public health consequences.
    • K. Mølbak
    • Biology, Medicine
    • Journal of veterinary medicine. B, Infectious diseases and veterinary public health
    • 2004
    • 162
    The role of antibiotics and antibiotic resistance in nature.
    • R. Aminov
    • Biology, Medicine
    • Environmental microbiology
    • 2009
    • 399
    Factors affecting the reversal of antimicrobial-drug resistance.
    • 126
    Antibiotic resistance-the need for global solutions.
    • 2,145
    • PDF