Understanding the mechanism of action of B12-dependent ethanolamine ammonia-lyase: synergistic interactions at play.


Ab initio molecular orbital calculations are used to examine the mechanism of action of B(12)-dependent ethanolamine ammonia-lyase involving the conversion of 2-aminoethanol to acetaldehyde plus ammonia. We attempt to elucidate the mechanism by which the enzyme facilitates this reaction through interactions between active-site residues and the substrate… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.