Understanding the fundamentals of perfluorocarbons and perfluorocarbon emulsions relevant to in vivo oxygen delivery.

@article{Riess2005UnderstandingTF,
  title={Understanding the fundamentals of perfluorocarbons and perfluorocarbon emulsions relevant to in vivo oxygen delivery.},
  author={Jean G. Riess},
  journal={Artificial cells, blood substitutes, and immobilization biotechnology},
  year={2005},
  volume={33 1},
  pages={47-63}
}
  • Jean G. Riess
  • Published 2005 in
    Artificial cells, blood substitutes, and…
The unique behavior of perfluorocarbons (PFCs), including their high oxygen dissolving capacity, hydrophobic and lipophobic character, and extreme inertness, derive directly, in a predictable manner, from the electronic structure and spatial requirements of the fluorine atom. Their low water solubility is key to the prolonged in vivo persistence of the now commercially available injectable microbubbles that serve as contrast agents for diagnostic ultrasound imaging. Oxygent, a stable, small… CONTINUE READING