Understanding the complexity of γδ T-cell subsets in mouse and human.

  title={Understanding the complexity of γδ T-cell subsets in mouse and human.},
  author={Dick John Pang and Joana F. Neves and Nital Sumaria and Daniel J Pennington},
  volume={136 3},
γδ T cells are increasingly recognized as having important functional roles in a range of disease scenarios such as infection, allergy, autoimmunity and cancer. With this has come realization that γδ cells are not a homogeneous population of cells with a single physiological role. Instead, ever increasing complexity in both phenotype and function is being ascribed to γδ cell subsets from various tissues and locations, and in both mouse and human. Here, we review this complexity by describing… CONTINUE READING
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