Understanding the complex pathobiology of high pathogenicity avian influenza viruses in birds.

  title={Understanding the complex pathobiology of high pathogenicity avian influenza viruses in birds.},
  author={David Swayne},
  journal={Avian diseases},
  volume={51 1 Suppl},
Avian influenza (AI) viruses are a diverse group of viruses that can be divided into 144 subtypes, based on different combinations of the 16 hemagglutinin and nine neuraminidase subtypes, and two pathotypes (low and high pathogenicity [HP]), based on lethality for the major poultry species, the chicken. However, other criteria are important in understanding the complex biology of AI viruses, including host adaptation, transmissibility, infectivity, tissue tropism, and lesion, and disease… CONTINUE READING
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