Understanding the cardiovascular actions of soy isoflavones: potential novel targets for antihypertensive drug development.

@article{Martin2008UnderstandingTC,
  title={Understanding the cardiovascular actions of soy isoflavones: potential novel targets for antihypertensive drug development.},
  author={Douglas S. Martin and Jin Song and Connie J. Mark and Kathleen M. Eyster},
  journal={Cardiovascular & hematological disorders drug targets},
  year={2008},
  volume={8 4},
  pages={
          297-312
        }
}
Interest in and use of "natural" remedies has grown exponentially in recent years. Compounds that have attracted considerable attention are the isoflavones, particular those found in soy. This review will provide a critical evaluation of our current understanding of the effects, mechanisms of action, and potential clinical applications of soy isoflavones in hypertension. Current data indicate that soy isoflavones, such as genistein and daidzein and equol, relax vascular smooth muscle both in… CONTINUE READING