Understanding the Y chromosome variation in Korea—relevance of combined haplogroup and haplotype analyses

@article{Park2012UnderstandingTY,
  title={Understanding the Y chromosome variation in Korea—relevance of combined haplogroup and haplotype analyses},
  author={Myung Jin Park and Hwan Young Lee and Woo Ick Yang and Kyoung-Jin Shin},
  journal={International Journal of Legal Medicine},
  year={2012},
  volume={126},
  pages={589-599}
}
We performed a molecular characterization of Korean Y-chromosomal haplogroups using a combination of Y-chromosomal single nucleotide polymorphisms (Y-SNPs) and Y-chromosomal short tandem repeats (Y-STRs). [] Key Result In a test using DNA samples from 706 Korean males, a total of 19 different haplogroups were identified by 26 Y-SNPs including the newly redefined markers (PK4, KL2, and P164) in haplogroup O. When genotyping the SNPs, phylogenetic nonequivalence was found between SNPs M117 and M133, which…

Analysis of 17 Y‐STR loci haplotype and Y‐chromosome haplogroup distribution in five Chinese ethnic groups

The 17 Y‐STR loci are highly polymorphic markers in the five groups and hence are very useful in forensic application, population genetics, and human evolution studies.

Taiwan Y-chromosomal DNA variation and its relationship with Island Southeast Asia

The geographic distribution and the diversity accumulated, support a pincer model of dispersals and gene flow from the mainland to the islands which likely started during the late upper Paleolithic, 18,000 to 15,000 years ago.

Characterisation of novel and rare Y-chromosome short tandem repeat alleles in self-declared South Australian Aboriginal database

Analysis of an in-house database of South Australian self-declared Aboriginal males held by Forensic Science South Australia using the Applied Biosystem’s AmpFℓSTR® Yfiler™ PCR Amplification Kit revealed 43 variant Y-STR alleles at 6 of the 17 loci.

Fine-Scale Genetic Structure and Natural Selection Signatures of Southwestern Hans Inferred From Patterns of Genome-Wide Allele, Haplotype, and Haplogroup Lineages

A case and ideal strategy is provided to reconstruct the detailed demographic evolutionary history of Guizhou Hans, which provided new insights into the fine-scale genomic formation of one ethnolinguistically specific targeted population from the comprehensive perspectives of the shared unlinked alleles, linked haplotypes, and paternal and maternal lineages.

Uniparental Genetic Analyses Reveal the Major Origin of Fujian Tanka from Ancient Indigenous Daic Populations

The interpopulation comparison revealed that the Fujian Tanka have a closer affinity with Daic populations than with Han Chinese in paternal lineages but are closely clustered with southern Han populations such as Hakka and Chaoshanese in maternal lineages.

References

SHOWING 1-10 OF 37 REFERENCES

Y‐chromosomal Binary Haplogroups in the Japanese Population and their Relationship to 16 Y‐STR Polymorphisms

The present data will enable researchers to connect data from binary haplogrouping in anthropological studies and Y‐STR typing in forensic studies in East Asian populations, especially those in and around Japan.

Analysis of Y-chromosomal SNP haplogroups and STR haplotypes in an Algerian population sample

The distribution of Y-chromosomal single nucleotide polymorphism (SNP) haplogroups and short tandem repeat (STR) haplotypes was determined in a sample of 102 unrelated men of Arab origin from

Y chromosome homogeneity in the Korean population

The survey shows that the present data of Korean individuals could be helpful to establish a comprehensive forensic reference database for frequency estimation.

High frequencies of Y-chromosome haplogroup O2b-SRY465 lineages in Korea: a genetic perspective on the peopling of Korea

The findings are consistent with linguistic, archaeological and historical evidence, which suggest that the direct ancestors of Koreans were proto-Koreans who inhabited the northeastern region of China and the Korean Peninsula during the Neolithic and Bronze Ages.

An updated tree of Y-chromosome Haplogroup O and revised phylogenetic positions of mutations P164 and PK4

The phylogenetic position of recently defined markers (L127, KL1, KL2, P164, and PK4) in the background of Haplogroup O is determined and this revision evidently improved the resolving power of Y-chromosome phylogeny in East Asia.

Excavating Y-chromosome haplotype strata in Anatolia

This comprehensive characterization of Y-chromosome heritage addresses many multifaceted aspects of Anatolian prehistory, including: the most frequent haplogroup, J, splits into two sub-clades, one of which (J2) shows decreasing variances with increasing latitude, compatible with a northward expansion.

Variation in short tandem repeats is deeply structured by genetic background on the human Y chromosome.

Genetic variability appears to be much more structured by lineage than by population, and the deep structure of the genetic variation in old genealogical units (haplogroups) challenges a population-based perspective in the comprehension of human genome diversity.

Y-chromosome short tandem repeat DYS458.2 non-consensus alleles occur independently in both binary haplogroups J1-M267 and R1b3-M405.

It is shown that the DYS458.2 allelic innovation arose independently on at least two distinctive binary haplogroup backgrounds and possibly a third as well and additional information for other linked polymorphic loci is required when using such non-conforming alleles to infer haplogroups background and common ancestry.

Y-chromosome short tandem repeat intermediate variant alleles DYS392.2, DYS449.2, and DYS385.2 delineate new phylogenetic substructure in human Y-chromosome haplogroup tree.

AIM To determine the human Y-chromosome haplogroup backgrounds of intermediate-sized variant alleles displayed by short tandem repeat (STR) loci DYS392, DYS449, and DYS385, and to evaluate the

Analysis of molecular variance (AMOVA) of Y-chromosome-specific microsatellites in two closely related human populations.

The analysis of seven Y-chromosome-specific microsatellite loci revealed a high level of polymorphism in two closely related human populations, allowing the characterization of the level of genetic distinctiveness of supposedly inbred or isolated populations and discrimination even between closely related populations.