Understanding the Effect of Ionic Liquids as Adjuvants in the Partition of Biomolecules in Aqueous Two-Phase Systems Formed by Polymers and Weak Salting-Out Agents.

@article{Neves2019UnderstandingTE,
  title={Understanding the Effect of Ionic Liquids as Adjuvants in the Partition of Biomolecules in Aqueous Two-Phase Systems Formed by Polymers and Weak Salting-Out Agents.},
  author={Catarina Maia Seco Seiça Neves and R. C. S. Sousa and Matheus M Pereira and Mara G Freire and Jo{\~a}o Ara{\'u}jo Pereira Coutinho},
  journal={Biochemical engineering journal},
  year={2019},
  volume={141},
  pages={
          239-246
        }
}
Ionic liquids (ILs) as adjuvants in polymer-salt aqueous two-phase systems (ATPS) have been used to improve the extraction of biomolecules. However, the impact of ILs as adjuvants on the partition of biomolecules is still poorly understood. Previous works mostly focused on ATPS based on strong salting-out agents, which may mask the IL effect. In this work, ATPS formed by polyethylene glycol (PEG 400) and a weak salting-out salt ((NH4)2SO4) with a wide number of ILs as adjuvants (chloride-based… CONTINUE READING

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