Understanding phenotype variability in frontotemporal lobar degeneration due to granulin mutation.

Abstract

Phenotype in patients with granulin (GRN) mutations is unpredictable, ranging from behavioral variant frontotemporal dementia (bvFTD) to agrammatic variant of primary progressive aphasia (avPPA). To date the wide clinical variability of FTLD-GRN remains unexplained. The aim of the study was to identify genetic pathways differentiating phenotypic expression… (More)
DOI: 10.1016/j.neurobiolaging.2013.10.097

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@article{Bonvicini2014UnderstandingPV, title={Understanding phenotype variability in frontotemporal lobar degeneration due to granulin mutation.}, author={Cristian Bonvicini and Elena Milanesi and Andrea Pilotto and Nadia Cattane and Enrico Premi and Silvana Archetti and Alessandro Padovani and Massimo Gennarelli and Barbara Borroni}, journal={Neurobiology of aging}, year={2014}, volume={35 5}, pages={1206-11} }