Understanding and treating pulmonary hypertension in congenital diaphragmatic hernia.

Abstract

Lung hypoplasia and pulmonary hypertension are classical features of congenital diaphragmatic hernia (CDH) and represent the main determinants of survival. The mechanisms leading to pulmonary hypertension in this malformation are still poorly understood, but may combine altered vasoreactivity, pulmonary artery remodeling, and a hypoplastic pulmonary… (More)
DOI: 10.1016/j.siny.2014.09.008

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