Understanding and modulating the Toll like Receptors (TLRs) and NOD like Receptors (NLRs) cross talk in type 2 diabetes.

@article{Prajapati2014UnderstandingAM,
  title={Understanding and modulating the Toll like Receptors (TLRs) and NOD like Receptors (NLRs) cross talk in type 2 diabetes.},
  author={Bhumika Prajapati and Prasant Kumar Jena and Parth Rajput and Kaveri Purandhar and Sriram Seshadri},
  journal={Current diabetes reviews},
  year={2014},
  volume={10 3},
  pages={190-200}
}
Obesity and Type 2 diabetes are leading health problems which are characterized by low-grade inflammation with an increase in inflammatory cytokines along with the change in the gut microbiota population. Toll like Receptors (TLRs) and NOD like Receptors (NLRs) are very prominent pathogen recognition receptors, which play a significant role in the innate immune system. Both TLRs and NLRs pathways are mediated through different adaptor proteins; commonly found to activate the NF-kB, which… CONTINUE READING
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