Understanding TB latency using computational and dynamic modelling procedures.

Abstract

The Mycobacterium tuberculosis bacilli's potency to cause persistent latent infection that is unresponsive to the current cocktail of TB drugs is strongly associated with its ability to adapt to changing intracellular environments, and tolerating, evading and subverting host defence mechanisms. We applied a combination of bioinformatics and mathematical… (More)
DOI: 10.1016/j.meegid.2012.09.017

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