Understanding Risk Factors for Opioid Overdose in Clinical Populations to Inform Treatment and Policy

  title={Understanding Risk Factors for Opioid Overdose in Clinical Populations to Inform Treatment and Policy},
  author={Tae Woo Park and Lewei Allison Lin and Avinash Hosanagar and Amanda Kogowski and Katie Paige and Amy S B Bohnert},
  journal={Journal of Addiction Medicine},
Overdoses involving opioid analgesics represent a significant public health problem in the United States. We reviewed the literature on risk factors for overdose, with a focus on studies that examine clinical populations of patients receiving opioids for pain and potential risk factors for overdose in these populations. A structured review resulted in 15 articles published between 2007 and 2015 that examined risk factors for fatal and nonfatal overdose in patients receiving opioid analgesics… 

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An analysis of the root causes for opioid-related overdose deaths in the United States.

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Risk factors for serious prescription opioid-related toxicity or overdose among Veterans Health Administration patients.

Screening patients for risk, providing education, and coprescribing naloxone for those at elevated risk may be effective at reducing serious opioid-related respiratory/CNS depression and overdose in medical users of prescription opioids.

Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges.

Assessing risk for drug overdose in a national cohort: role for both daily and total opioid dose?

  • Yuanyuan LiangB. Turner
  • Medicine, Psychology
    The journal of pain : official journal of the American Pain Society
  • 2015

CDC Guideline for Prescribing Opioids for Chronic Pain--United States, 2016.

This guideline is intended to improve communication about benefits and risks of opioids for chronic pain, improve safety and effectiveness of pain treatment, and reduce risks associated with long-term opioid therapy.

Opioid dose and drug-related mortality in patients with nonmalignant pain.

Among patients receiving opioids for nonmalignant pain, the daily dose is strongly associated with opioid-related mortality, particularly at doses exceeding thresholds recommended in recent clinical guidelines.

Reasons for under-use of prescribed opioid medications by patients in pain.

Improved communication between patients and providers and shared decision-making regarding opioid prescriptions may improve pain management and minimize the problems associated with over-prescription of opioids.

Association of Care Practices with Suicide Attempts in US Veterans Prescribed Opioid Medications for Chronic Pain Management

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