Understanding Past Population Dynamics: Bayesian Coalescent-Based Modeling with Covariates.

  title={Understanding Past Population Dynamics: Bayesian Coalescent-Based Modeling with Covariates.},
  author={M. Gill and P. Lemey and S. Bennett and R. Biek and M. Suchard},
  journal={Systematic biology},
  volume={65 6},
  • M. Gill, P. Lemey, +2 authors M. Suchard
  • Published 2016
  • Computer Science, Mathematics, Biology, Medicine
  • Systematic biology
  • Effective population size characterizes the genetic variability in a population and is a parameter of paramount importance in population genetics and evolutionary biology. Kingman's coalescent process enables inference of past population dynamics directly from molecular sequence data, and researchers have developed a number of flexible coalescent-based models for Bayesian nonparametric estimation of the effective population size as a function of time. Major goals of demographic reconstruction… CONTINUE READING
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