Understanding LTP in pain pathways

  title={Understanding LTP in pain pathways},
  author={J{\"u}rgen Sandk{\"u}hler},
  journal={Molecular Pain},
  pages={9 - 9}
Long-term potentiation (LTP) at synapses of nociceptive nerve fibres is a proposed cellular mechanism underlying some forms of hyperalgesia. In this review fundamental properties of LTP in nociceptive pathways are described. The following topics are specifically addressed: A concise definition of LTP is given and a differentiation is made between LTP and "central sensitisation". How to (and how not to) measure and how to induce LTP in pain pathways is specified. The signal transduction pathways… CONTINUE READING
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