Understanding Aspects of Aluminum Exposure in Alzheimer's Disease Development

@article{Kandimalla2016UnderstandingAO,
  title={Understanding Aspects of Aluminum Exposure in Alzheimer's Disease Development},
  author={R. Kandimalla and Jayalakshmi Vallamkondu and Edwin B. Corgiat and K. Gill},
  journal={Brain Pathology},
  year={2016},
  volume={26}
}
Aluminum is a ubiquitously abundant nonessential element. Aluminum has been associated with neurodegenerative diseases such as Alzheimer's disease (AD), amyotrophic lateral sclerosis, and dialysis encephalopathy. Many continue to regard aluminum as controversial although increasing evidence supports the implications of aluminum in the pathogenesis of AD. Aluminum causes the accumulation of tau protein and Aβ protein in the brain of experimental animals. Aluminum induces neuronal apoptosis in… Expand
55 Citations
Therapeutics of Neurotransmitters in Alzheimer's Disease.
  • 47
Aluminum in neurological disease – a 36 year multicenter study
  • 11
  • PDF
Aluminum-Induced Neural Cell Death.
  • Q. Zhang
  • Biology, Medicine
  • Advances in experimental medicine and biology
  • 2018
  • 5
Effect of aluminum combined with ApoEε4 on Tau phosphorylation and Aβ deposition.
  • Yanni Wang, Huan Li, +9 authors Q. Niu
  • Chemistry, Medicine
  • Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements
  • 2020
Zinc Improves Cognitive and Neuronal Dysfunction During Aluminium-Induced Neurodegeneration
  • 23
Unusual neuropathological features and increased brain aluminium in a resident of Camelford, UK
  • 3
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 184 REFERENCES
Effects of aluminum on the nervous system and its possible link with neurodegenerative diseases.
  • M. Kawahara
  • Medicine
  • Journal of Alzheimer's disease : JAD
  • 2005
  • 212
Aluminum as a toxicant
  • 223
  • Highly Influential
The role of metals in the etiology of Alzheimer's disease.
  • 143
Aluminum in the diet and Alzheimer's disease: from current epidemiology to possible disease-modifying treatment.
  • 36
Neurofibrillary pathology and aluminum in Alzheimer's disease.
  • 37
Mechanisms of aluminum-induced neurodegeneration in animals: Implications for Alzheimer's disease.
  • 81
Can the controversy of the role of aluminum in Alzheimer's disease be resolved? What are the suggested approaches to this controversy and methodological issues to be considered?
  • 151
  • Highly Influential
Aluminum modulates brain amyloidosis through oxidative stress in APP transgenic mice
  • 230
...
1
2
3
4
5
...