Underlying molecular and cellular mechanisms in childhood irritable bowel syndrome

Abstract

Irritable bowel syndrome (IBS) affects a large number of children throughout the world. The symptom expression of IBS is heterogeneous, and several factors which may be interrelated within the IBS biopsychosocial model play a role. These factors include visceral hyperalgesia, intestinal permeability, gut microbiota, psychosocial distress, gut inflammation… (More)
DOI: 10.1186/s40348-016-0036-8

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