Underlying brain mechanisms that regulate sleep-wakefulness cycles.

@article{Gvilia2010UnderlyingBM,
  title={Underlying brain mechanisms that regulate sleep-wakefulness cycles.},
  author={Irma Gvilia},
  journal={International review of neurobiology},
  year={2010},
  volume={93},
  pages={
          1-21
        }
}
Daily cycles of wakefulness and sleep are regulated by coordinated interactions between wakefulness- and sleep-regulating neural circuitry. Wakefulness is associated with neuronal activity in cholinergic neurons in the brainstem and basal forebrain, monoaminergic neurons in the brainstem and posterior hypothalamus, and hypocretin (orexin) neurons in the lateral hypothalamus that act in a coordinated manner to stimulate cortical activation on the one hand and behavioral arousal on the other hand… CONTINUE READING

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