Undercarboxylated osteocalcin is positively associated with free testosterone in male patients with type 2 diabetes mellitus

@article{Kanazawa2012UndercarboxylatedOI,
  title={Undercarboxylated osteocalcin is positively associated with free testosterone in male patients with type 2 diabetes mellitus},
  author={Ippei Kanazawa and Kiyoshi Tanaka and Norihiko Ogawa and Mika Yamauchi and Toru Yamaguchi and Toshitsugu Sugimoto},
  journal={Osteoporosis International},
  year={2012},
  volume={24},
  pages={1115-1119}
}
Although a recent study showed that undercarboxylated osteocalcin (ucOC) is important for male fertility and testosterone production by testes, little is known about the relationship between ucOC and testosterone in humans. We found for the first time that ucOC is positively associated with free testosterone in men with type 2 diabetes. The ucOC has been shown to play a key role in energy metabolism as an endocrine hormone. Although a recent animal study demonstrated that ucOC is also important… CONTINUE READING
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