Under-utilization of evidence-based drug treatment in patients with heart failure is only partially explained by dissimilarity to patients enrolled in landmark trials: a report from the Euro Heart Survey on Heart Failure.

@article{Lenzen2005UnderutilizationOE,
  title={Under-utilization of evidence-based drug treatment in patients with heart failure is only partially explained by dissimilarity to patients enrolled in landmark trials: a report from the Euro Heart Survey on Heart Failure.},
  author={Mattie J. Lenzen and Eric Boersma and Wilma J. M. Scholte Op Reimer and Aggie H. M. M. Balk and Michel Komajda and Karl Swedberg and Ferenc Follath and Manuel Jim{\'e}nez-Navarro and Maarten L. Simoons and John G. F. Cleland},
  journal={European heart journal},
  year={2005},
  volume={26 24},
  pages={2706-13}
}
AIMS Surveys on heart failure management suggest under-utilization of life-saving evidence-based treatment. Evidence-based medicine and clinical guidelines are based on the results of randomized controlled trials. Therefore, we investigated how patients who fulfilled the enrolment criteria of randomized trials were treated in real life. METHODS AND RESULTS We selected three large placebo-controlled trials of patients with chronic heart failure, in which ACE-inhibitors (ACE-Is), beta-blockers… CONTINUE READING

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