Uncovering the mechanism(s) of action of deep brain stimulation: activation, inhibition, or both.

@article{McIntyre2004UncoveringTM,
  title={Uncovering the mechanism(s) of action of deep brain stimulation: activation, inhibition, or both.},
  author={Cameron C. McIntyre and Marc Savasta and Lydia Kerkerian-Le Goff and Jerrold L. Vitek},
  journal={Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology},
  year={2004},
  volume={115 6},
  pages={1239-48}
}
High-frequency deep brain stimulation (DBS) of the thalamus or basal ganglia represents an effective clinical technique for the treatment of several medically refractory movement disorders. However, understanding of the mechanisms responsible for the therapeutic action of DBS remains elusive. The goal of this review is to address our present knowledge of… CONTINUE READING