Uncovering the clinical utility of miR-143, miR-145 and miR-224 for predicting the survival of bladder cancer patients following treatment.

@article{Avgeris2015UncoveringTC,
  title={Uncovering the clinical utility of miR-143, miR-145 and miR-224 for predicting the survival of bladder cancer patients following treatment.},
  author={Margaritis Avgeris and Konstantinos Mavridis and Theodoros Tokas and Konstantinos G. Stravodimos and Emmanuel G. Fragoulis and Andreas Scorilas},
  journal={Carcinogenesis},
  year={2015},
  volume={36 5},
  pages={528-37}
}
Accurate prognosis is a key factor in establishing optimal therapeutic decisions; yet in the case of bladder cancer (BlCa) current prognostic indicators cannot ensure optimal disease management. Here, we aimed to evaluate the previously unexplored clinical potential of the urological cancer-related miR-145, miR-143 and miR-224 in BlCa. A total of 279 bladder tissue specimens were included in this study (133 BlCa, 107 adjacent normal and 39 healthy samples). Total RNA was extracted from tissues… CONTINUE READING

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