Uncovering the Role of Oxidative Imbalance in the Development and Progression of Bronchial Asthma

  title={Uncovering the Role of Oxidative Imbalance in the Development and Progression of Bronchial Asthma},
  author={Luiz Henrique C Vasconcelos and Sarah R D Ferreira and Maria da C C Silva and Paula Benvindo Ferreira and Iara Le{\~a}o Luna de Souza and Fabiana de Andrade Cavalcante and Bagn{\'o}lia Ara{\'u}jo da Silva},
  journal={Oxidative Medicine and Cellular Longevity},
Asthma is a chronic inflammatory disease of the airways related to epithelial damage, bronchial hyperresponsiveness to contractile agents, tissue remodeling, and luminal narrowing. Currently, there are many data about the pathophysiology of asthma; however, a new aspect has emerged related to the influence of reactive oxygen and nitrogen species (ROS and RNS) on the origin of this disease. Several studies have shown that an imbalance between the production of ROS and RNS and the antioxidant… 

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