Uncovering obsessive-compulsive disorder risk genes in a pediatric cohort by high-resolution analysis of copy number variation

@inproceedings{Gazzellone2016UncoveringOD,
  title={Uncovering obsessive-compulsive disorder risk genes in a pediatric cohort by high-resolution analysis of copy number variation},
  author={Matthew J. Gazzellone and Mehdi Zarrei and Christie L Burton and Susan Walker and Mohammed Uddin and Sabry M. Shaheen and Julie Coste and Rageen Rajendram and Reva J. Schachter and Marlena Colasanto and Gregory L Hanna and David R. Rosenberg and Noam Soreni and Kate Dimond Fitzgerald and Christian R Marshall and Janet A. Buchanan and Daniele Merico and Paul Daniel Arnold and Stephen W. Scherer},
  booktitle={Journal of Neurodevelopmental Disorders},
  year={2016}
}
Obsessive-compulsive disorder (OCD) is a heterogeneous neuropsychiatric condition, thought to have a significant genetic component. When onset occurs in childhood, affected individuals generally exhibit different characteristics from adult-onset OCD, including higher prevalence in males and increased heritability. Since neuropsychiatric conditions are associated with copy number variations (CNVs), we considered their potential role in the etiology of OCD. We genotyped 307 unrelated pediatric… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 4 times over the past 90 days. VIEW TWEETS

References

Publications referenced by this paper.
Showing 1-10 of 64 references

official journal of the American College of Medical Genetics

  • M Uddin, B Thiruvahindrapuram, +4 authors medicine population genetics. Genetics in
  • 2014. doi:10.1038/gim.2014.178. Gazzellone et al…
  • 2016
2 Excerpts

Similar Papers

Loading similar papers…