Uncovering multiloci-ordering by algebraic property of Laplacian matrix and its Fiedler vector


MOTIVATION The loci-ordering, based on two-point recombination fractions for a pair of loci, is the most important step in constructing a reliable and fine genetic map. RESULTS Using the concept from complex graph theory, here we propose a Laplacian ordering approach which uncovers the loci-ordering of multiloci simultaneously. The algebraic property for… (More)
DOI: 10.1093/bioinformatics/btv669


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