Uncoupling protein-3 expression in rodent skeletal muscle is modulated by food intake but not by changes in environmental temperature.

@article{Boss1998UncouplingPE,
  title={Uncoupling protein-3 expression in rodent skeletal muscle is modulated by food intake but not by changes in environmental temperature.},
  author={Olivier Boss and Sonia Samec and Françoise Kuehne and Philippe Bijlenga and Françoise Assimacopoulos-Jeannet and Josiane Seydoux and Jean Paul Giacobino and Patrick Muzzin},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 1},
  pages={
          5-8
        }
}
A new member of the uncoupling protein (UCP) family called UCP3 has recently been cloned and shown to be highly expressed in skeletal muscle of rodents and humans. In the present study, UCP3 was overexpressed in C2C12 myoblasts where it acts as an uncoupling protein. Changes in UCP3 mRNA expression were examined in rodent muscles under conditions known to modulate thermogenesis in brown adipose tissue. In skeletal muscle, UCP3 expression did not change in response to 48 h of cold exposure (6… CONTINUE READING

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