Uncoupling of proliferation and Stat5 activation in thymic stromal lymphopoietin-mediated signal transduction.

Abstract

Thymic stromal lymphopoietin (TSLP) is a cytokine that facilitates B lymphocyte differentiation and costimulates T cells. Previous studies have demonstrated that a functional TSLP receptor complex is a heterodimer consisting of the TSLP receptor and the IL-7R alpha-chain. TSLP-mediated signaling is unique among members of the cytokine receptor family in… (More)

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Cite this paper

@article{Isaksen2002UncouplingOP, title={Uncoupling of proliferation and Stat5 activation in thymic stromal lymphopoietin-mediated signal transduction.}, author={Deborah E. Isaksen and Heinz Baumann and Baohua Zhou and Sebastien Nivollet and Andrew G. Farr and Steven D. Levin and Steven F. Ziegler}, journal={Journal of immunology}, year={2002}, volume={168 7}, pages={3288-94} }