Uncoupling of neurodegeneration and gliosis in a murine model of juvenile cortical lesion.

Abstract

A small experimental cryolesion to the right parietal cortex of juvenile mice causes late-onset global brain atrophy with memory impairments, reminiscent of cognitive decline, and progressive brain matter loss in schizophrenia. However, the cellular events underlying this global neurodegeneration are not understood. Here we show, based on comprehensive… (More)
DOI: 10.1002/glia.20797

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