Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants

@inproceedings{Bansala2015UncouplingLA,
  title={Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants},
  author={Ankita Bansala and Lihua J. Zhua and Kelvin Yena and Heidi A. Tissenbauma},
  year={2015}
}
  • Ankita Bansala, Lihua J. Zhua, +1 author Heidi A. Tissenbauma
  • Published 2015
Aging research has been very successful at identifying signaling pathways and evolutionarily conserved genes that extend lifespan with the assumption that an increase in lifespan will also increase healthspan. However, it is largely unknown whether we are extending the healthy time of life or simply prolonging a period of frailty with increased incidence of age-associated diseases. Here we use Caenorhabditis elegans, one of the premiere systems for lifespan studies, to determine whether… CONTINUE READING