Uncoupling Protein 1 of Brown Adipocytes, the Only Uncoupler: A Historical Perspective

Abstract

Uncoupling protein 1 (UCP1), is a unique mitochondrial membranous protein devoted to adaptive thermogenesis, a specialized function performed by brown adipocytes. Whereas the family of mitochondrial metabolite carriers comprises ∼40 members, UCP1 is the only memberable to translocate protons through the inner membrane of brown adipocyte mitochondria. By… (More)
DOI: 10.3389/fendo.2011.00085

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