Unconventional Secretion of Heat Shock Proteins in Cancer

@inproceedings{Santos2017UnconventionalSO,
  title={Unconventional Secretion of Heat Shock Proteins in Cancer},
  author={Tiago G{\'o}ss Santos and Vilma Regina Martins and Glaucia Noeli Maroso Hajj},
  booktitle={International journal of molecular sciences},
  year={2017}
}
Heat shock proteins (HSPs) are abundant cellular proteins involved with protein homeostasis. They have both constitutive and inducible isoforms, whose expression levels are further increased by stress conditions, such as temperature elevation, reduced oxygen levels, infection, inflammation and exposure to toxic substances. In these situations, HSPs exert a pivotal role in offering protection, preventing cell death and promoting cell recovery. Although the majority of HSPs functions are exerted… CONTINUE READING
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