Uncontrolled Innate and Impaired Adaptive Immune Responses in Patients with COVID-19 Acute Respiratory Distress Syndrome

@article{Hue2020UncontrolledIA,
  title={Uncontrolled Innate and Impaired Adaptive Immune Responses in Patients with COVID-19 Acute Respiratory Distress Syndrome},
  author={Sophie Hue and Asma Beldi-Ferchiou and In{\'e}s Bendib and Mathieu Sur{\'e}naud and Slim Fourati and T Frapard and Simon Rivoal and Keyvan Razazi and Guillaume Carteaux and Marie-H{\'e}l{\`e}ne Delfau-Larue and Armand Mekontso-Dessap and Etienne Audureau and Nicolas de Prost},
  journal={American Journal of Respiratory and Critical Care Medicine},
  year={2020},
  volume={202},
  pages={1509 - 1519}
}
Rationale: Uncontrolled inflammatory innate response and impaired adaptive immune response are associated with clinical severity in patients with coronavirus disease (COVID-19). Objectives: To compare the immunopathology of COVID-19 acute respiratory distress syndrome (ARDS) with that of non–COVID-19 ARDS, and to identify biomarkers associated with mortality in patients with COVID-19 ARDS. Methods: Prospective observational monocenter study. Immunocompetent patients diagnosed with RT-PCR… 

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