Uncoiling CNLs: Structure/Function Approaches to Understanding CC Domain Function in Plant NLRs

@article{Bentham2018UncoilingCS,
  title={Uncoiling CNLs: Structure/Function Approaches to Understanding CC Domain Function in Plant NLRs},
  author={Adam R. Bentham and Rafał Zdrzałek and Juan Carlos De la Concepcion and Mark J. Banfield},
  journal={Plant and Cell Physiology},
  year={2018},
  volume={59},
  pages={2398 - 2408}
}
Abstract Plant nucleotide-binding leucine-rich repeat receptors (NLRs) are intracellular pathogen receptors whose N-terminal domains are integral to signal transduction after perception of a pathogen-derived effector protein. The two major plant NLR classes are defined by the presence of either a Toll/interleukin-1 receptor (TIR) or a coiled-coil (CC) domain at their N-terminus (TNLs and CNLs). Our knowledge of how CC domains function in plant CNLs lags behind that of how TIR domains function… 

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