Unchanged in vivo P50 at high altitude despite decreased erythrocyte age and elevated 2,3-diphosphoglycerate.

@article{Mairburl1990UnchangedIV,
  title={Unchanged in vivo P50 at high altitude despite decreased erythrocyte age and elevated 2,3-diphosphoglycerate.},
  author={Heimo Mairb{\"a}url and Wolfgang Schobersberger and Oswald Oelz and Peter D B{\"a}rtsch and Kai Uwe Eckardt and Christian R. K. D. Bauer},
  journal={Journal of applied physiology},
  year={1990},
  volume={68 3},
  pages={1186-94}
}
We measured hematological and erythrocyte O2 transport parameters in whole blood and density-separated erythrocytes in 11 mountaineers before and during 5 days of exposure to high altitude (4,559 m). We determined the in vivo (arterial pHblood and PCO2) and standard (pHblood = 7.4, PCO2 = 40 Torr) O2 tension at 50% O2 saturation of hemoglobin and (P50,vv and P50,st) and Bohr coefficients (BC) for fixed acid (H+) and CO2 and examined the contribution of the altered average age of circulating… CONTINUE READING

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