Uncertainty, Neuromodulation, and Attention

  title={Uncertainty, Neuromodulation, and Attention},
  author={Angela J. Yu and Peter Dayan},
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistical framework, optimal inference and prediction, based on unreliable observations in changing contexts, require the representation and manipulation of different forms of uncertainty. We propose that the neuromodulators acetylcholine and norepinephrine play a major role in the brain's implementation of these uncertainty computations. Acetylcholine signals expected uncertainty, coming from known… CONTINUE READING
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