Uncapping of viral messenger RNA by phosphodiesterase of fibroblast plasma membranes


Isolated plasma membranes from mouse fibroblast lines 3T3 and its tranformant SV-3T3 contain a phosphodiesterase (oligonucleotidase, E.C.; nucleotide pyrophosphatase, E.C. that splits capped and methylated messenger RNA obtained from both reovirus and vesicular stomatitis virus. The isolated membranes are free of demonstrable ribonuclease… (More)
DOI: 10.1007/BF01868947


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