Unbinding of targeted ultrasound contrast agent microbubbles by secondary acoustic forces.

@article{Garbin2011UnbindingOT,
  title={Unbinding of targeted ultrasound contrast agent microbubbles by secondary acoustic forces.},
  author={Valeria Garbin and M. Overvelde and Benjamin Dollet and Nico de Jong and Detlef Lohse and Michel Versluis},
  journal={Physics in medicine and biology},
  year={2011},
  volume={56 19},
  pages={6161-77}
}
Targeted molecular imaging with ultrasound contrast agent microbubbles is achieved by incorporating targeting ligands on the bubble coating and allows for specific imaging of tissues affected by diseases. Improved understanding of the interplay between the acoustic forces acting on the bubbles during insonation with ultrasound and other forces (e.g. shear due to blood flow, binding of targeting ligands to receptors on cell membranes) can help improve the efficacy of this technique. This work… CONTINUE READING