Unbiased estimate of hippocampal granule cell numbers in hypothyroid and in sex-age-matched control rats.

@article{Madeira1988UnbiasedEO,
  title={Unbiased estimate of hippocampal granule cell numbers in hypothyroid and in sex-age-matched control rats.},
  author={Maria Dulce Cordeiro Madeira and Manuel Maria Paula-Barbosa and Ant{\'o}nio Cadete-Leite and Mar{\'i}a Tavares},
  journal={Journal fur Hirnforschung},
  year={1988},
  volume={29 6},
  pages={643-50}
}
Despite the similarities in the processes of cell acquisition between the hippocampal and cerebellar granular layers, it was suggested that changes induced by thyroid deficiency on the neurogenesis of their granule cells were region specific, leading to different end-results: a permanent decrease in the number of the dentate gyrus granule cells in hypothyroids, conversely to what occurs in the cerebellum, where their number is similar to those of controls or even increased. We decided to re… CONTINUE READING

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