Unawareness of motor phenoconversion in Huntington disease.

@article{McCusker2013UnawarenessOM,
  title={Unawareness of motor phenoconversion in Huntington disease.},
  author={E. A. McCusker and David G Gunn and Eric A. Epping and Clement T. Loy and Kylie Radford and Jane Johnston Griffith and James A. Mills and Jeffrey D. Long and Jane S. Paulsen},
  journal={Neurology},
  year={2013},
  volume={81 13},
  pages={1141-7}
}
OBJECTIVE To determine whether Huntington disease (HD) mutation carriers have motor symptoms (complaints) when definite motor onset (motor phenoconversion) is diagnosed and document differences between the groups with and without unawareness of motor signs. METHODS We analyzed data from 550 HD mutation carriers participating in the multicenter PREDICT-HD Study followed through the HD prodrome. Data analysis included demographics, the Unified Huntington's Disease Rating Scale (UHDRS) and the… CONTINUE READING
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