Umbilical cord mesenchymal stem cells inhibit the differentiation of circulating T follicular helper cells in patients with primary Sjögren's syndrome through the secretion of indoleamine 2,3-dioxygenase.

Abstract

OBJECTIVE The aim of this study was to investigate the effect of umbilical cord mesenchymal stem cells (UC-MSCs) on circulating T follicular helper (cTfh) cells in primary SS (pSS) patients. METHODS The percentage of CXCR5(+)PD-1(+)CD4(+) T cells in peripheral blood mononuclear cells (PBMCs) was analysed by flow cytometry. PBMCs were co-cultured with UC… (More)
DOI: 10.1093/rheumatology/keu316

Topics

6 Figures and Tables

Cite this paper

@article{Liu2015UmbilicalCM, title={Umbilical cord mesenchymal stem cells inhibit the differentiation of circulating T follicular helper cells in patients with primary Sj{\"o}gren's syndrome through the secretion of indoleamine 2,3-dioxygenase.}, author={Rui Liu and Dinglei Su and Min Zhou and Xuebing Feng and Xia Chong Li and Lingyun Sun}, journal={Rheumatology}, year={2015}, volume={54 2}, pages={332-42} }