Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus.

@article{Sun2010UmbilicalCM,
  title={Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus.},
  author={L. Sun and Dandan Wang and J. Liang and H. Zhang and X. Feng and Hong Wang and B. Hua and Bujun Liu and Shengqin Ye and Xiang Hu and Wenrong Xu and X. Zeng and Y. Hou and G. Gilkeson and R. Silver and L. Lu and S. Shi},
  journal={Arthritis and rheumatism},
  year={2010},
  volume={62 8},
  pages={
          2467-75
        }
}
OBJECTIVE Umbilical cord (UC)-derived mesenchymal stem cells (MSCs) have shown marked therapeutic effects in a number of diseases in animal studies, based on their potential for self-renewal and differentiation. No data are available on the effectiveness of UC MSC transplantation (MSCT) in human autoimmune disease. This study was undertaken to assess the efficacy and safety of allogeneic UC MSCT in patients with severe and treatment-refractory systemic lupus erythematosus (SLE). METHODS We… Expand
372 Citations

Paper Mentions

Interventional Clinical Trial
This study will explore safety and efficacy of allogeneic umbilical cord (UC) derived mesenchymal stem cells transplantation (MSCT) to treat patients with active and refractory… Expand
ConditionsSystemic Lupus Erythematosus
InterventionBiological
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