• DOI:10.1002/art.27548
Corpus ID: 6129443

Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus.

@article{Sun2010UmbilicalCM,
  title={Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus.},
  author={L. Sun and Dandan Wang and J. Liang and H. Zhang and X. Feng and Hong Wang and B. Hua and Bujun Liu and Shengqin Ye and Xiang Hu and Wenrong Xu and X. Zeng and Y. Hou and G. Gilkeson and R. Silver and L. Lu and S. Shi},
  journal={Arthritis and rheumatism},
  year={2010},
  volume={62 8},
  pages={
          2467-75
        }
}

• L. Sun, Dandan Wang, +14 authors S. Shi
• Published 2010
• Medicine
• Arthritis and rheumatism

OBJECTIVE Umbilical cord (UC)-derived mesenchymal stem cells (MSCs) have shown marked therapeutic effects in a number of diseases in animal studies, based on their potential for self-renewal and differentiation. No data are available on the effectiveness of UC MSC transplantation (MSCT) in human autoimmune disease. This study was undertaken to assess the efficacy and safety of allogeneic UC MSCT in patients with severe and treatment-refractory systemic lupus erythematosus (SLE). METHODS We… Expand

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