Umbilical cord blood as an alternative source of reduced-intensity hematopoietic stem cell transplantation for chronic Epstein-Barr virus-associated T or natural killer cell lymphoproliferative diseases.

@article{Sawada2014UmbilicalCB,
  title={Umbilical cord blood as an alternative source of reduced-intensity hematopoietic stem cell transplantation for chronic Epstein-Barr virus-associated T or natural killer cell lymphoproliferative diseases.},
  author={Akihisa Sawada and Masazumi Inoue and Maho Koyama-Sato and Osamu Kondo and Kayo Yamada and Mariko Shimizu and Kanako Isaka and Tomiko Kimoto and Haruhiko Kikuchi and Sadao Tokimasa and Masahiro Yasui and Keisei Kawa},
  journal={Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation},
  year={2014},
  volume={20 2},
  pages={
          214-21
        }
}
Chronic Epstein-Barr virus-associated T/natural killer cell lymphoproliferative diseases represented by chronic active Epstein-Barr virus infection are lethal but are curable with several courses of chemotherapy and allogeneic hematopoietic stem cell transplantation (HSCT). Recently, we reported that reduced-intensity conditioning (RIC) provided better outcomes than myeloablative conditioning because RIC was less toxic. However, it was unclear whether cord blood transplantation (CBT) works in… CONTINUE READING