Umbelliferone stimulated melanogenesis and increased glutathione level in B16F10 cells


Umbelliferone (7-hydroxycoumarin) treatment caused an increase in melanin content in B16F10 melanoma cells in a dose-dependent manner, without causing toxicity. The increase in melanin content was correlated with increases in the activity of tyrosinase, the rate-limiting enzyme in melanin synthesis, and the expressions of melanogenic proteins, including… (More)
DOI: 10.1007/s13530-017-0316-2


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