Ultraviolet radiation and nanoparticle induced intracellular free radicals generation measured in human keratinocytes by electron paramagnetic resonance spectroscopy.

@article{Rancan2014UltravioletRA,
  title={Ultraviolet radiation and nanoparticle induced intracellular free radicals generation measured in human keratinocytes by electron paramagnetic resonance spectroscopy.},
  author={Fiorenza Rancan and Berouz Nazemi and Sandro Rautenberg and Martin Ryll and Sabrina Hadam and Qi Gao and Steffen Hackbarth and Stefan Haag and Christina Graf and Eckart R{\"u}hl and Ulrike Blume-Peytavi and Juergen Lademann and Annika Vogt and Martina Claudia Meinke},
  journal={Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging},
  year={2014},
  volume={20 2},
  pages={182-93}
}
BACKGROUND Several nanoparticle-based formulations used in cosmetics and dermatology are exposed to sunlight once applied to the skin. Therefore, it is important to study possible synergistic effects of nanoparticles and ultraviolet radiation. METHODS Electron paramagnetic resonance spectroscopy (EPR) was used to detect intracellular free radicals induced by ultraviolet B (UVB) radiation and amorphous silica nanoparticle and to evaluate the influence of nanoparticle surface chemistry on… CONTINUE READING

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