Ultrastructure of the water-clear cell in the parathyroid gland of SAMP6 mice.

@article{Chen2006UltrastructureOT,
  title={Ultrastructure of the water-clear cell in the parathyroid gland of SAMP6 mice.},
  author={Huayue Chen and Shoichi Emura and Shizuko Shoumura},
  journal={Tissue & cell},
  year={2006},
  volume={38 3},
  pages={187-92}
}
Although the parathyroid water-clear cell is very rare, it has clinical significance because of its association with parathyroid hyperplasia or adenoma. SAMP6, a substrain of senescence-accelerated mouse, was developed as an animal model for senile osteoporosis. We investigated the morphology of the parathyroid glands in SAMP6 and age-matched normal mouse SAMR1. The parathyroid water-clear cells, which contained numerous vacuoles and the crystalloid inclusions, were found in SAMP6 mice at 5, 8… CONTINUE READING