Ultrastructure of the vasculature of central nervous system tumors of childhood.

  title={Ultrastructure of the vasculature of central nervous system tumors of childhood.},
  author={David G. Mclone},
  journal={Child's brain},
  volume={6 5},
Developing cell systems involving the central nervous system are ultimately dependent upon acquisition of a vascular supply for continued growth. Tumor cells proliferate to a critical mass beyond which metabolic exchange cannot be maintained by diffusion alone. The growth of this blood supply is stimulated by the tumor and grows into the cell mass from the surrounding brain. These 'tumor vessels' have anomalies of structure and function which explain many pathological changes seen in brain… CONTINUE READING

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