Ultrastructure of the attachment of Cryptosporidium sporozoites to tissue culture cells

  title={Ultrastructure of the attachment of Cryptosporidium sporozoites to tissue culture cells},
  author={Richard S Lumb and Kirby D. Smith and Peter J O'Donoghue and J. A. Lanser},
  journal={Parasitology Research},
The attachment of Cryptosporidium sporozoites to Madin-Darby canine kidney (MDCK) cells was examined using transmission electron microscopy. As the anterior end of the sporozoite came into close proximity to the MDCK cell, the host cell membrane evaginated around the sporozoite, forming a parasitophorous vacuole. A dense band formed below the host cell membrane at the site nearest to the conoid. Variably electron-dense material was apparently released from the conoid and a large membrane-bound… CONTINUE READING


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